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A medical review before starting treatment is essential

doi: 10.1249/mss.0000000000000852 78

& Ayton, S

Other key signaling pathways that are utilized are the mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/mTOR) pathways, as well as SH2B1, a scaffold protein that interacts with JAK2 and mediates GH-induced changes in the cytoskeleton