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Metformin, commonly prescribed for diabetes, and proton pump inhibitors used for acid reflux can both reduce B12 absorption over time

Some patients stay at 0.5mg long-term if their diabetes is well-controlled at that level

Those aged 65 and older have the third-highest rate of reported usage of GLP-1 drugs for weight loss (11.1%) and in increased usage since the first quarter of 2024 (6.5 points) among the five age groups but (as noted above) show no reduction in obesity since 2022

The human B 12 trafficking protein CblC processes nitrocobalamin

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