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Prepare for the first visit by having open conversations about what to expect and deciding whether a parent or caregiver will be in the room

Current evidence supports a multifactorial etiology in which more than 90 susceptibility loci, rare monogenic variants (e.g., LRRK2, SNCA, PRKN, and PINK1) and environmental toxicants (pesticides, heavy metals, and solvents) converge on three inter-related pathological hallmarks: oxidative stress, mitochondrial dysfunction and chronic neuroinflammation

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Uncontrolled hypothyroidism is linked to a higher incidence of obstetric complications, including gestational hypertension, preeclampsia, preterm birth, placental abruption, and postpartum hemorrhage [2, 11]

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However, there may be limitations in treating comorbid conditions like sleep-related breathing disorders