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In a meta-analysis study of 48,674 patients, researchers found that the average risk of post-endoscopy aspiration pneumonia was 1.9% with various risk factors identified, including old age 65 years, coexisting pulmonary disease, coexisting cerebrovascular disease, remnant stomach, sedation with propofol, and long procedural duration

Whilst one meta-analysis of 24 RCTs found a decrease in the pro-inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6), 15 the other (based on 28 studies) found a decrease in interleukin-8 (IL-8) when pooling all data and a decrease in IL-6 in a subset of studies using a dose of 1200 mg NAC per day or less, but no difference in CRP

dosing resumes at the next scheduled time

These studies were heterogeneous in terms of design, group definitions, and outcome measures

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