First, we emulated two cardiovascular outcome trials, SUSTAIN-6 (semaglutide versus sitagliptin as placebo proxy) and SURPASS-CVOT (tirzepatide versus dulaglutide), to benchmark and critically evaluate our design, data and analytic framework
Your provider may recommend temporarily reducing the dose, taking additional anti-nausea medication, or adjusting your titration schedule
"We are very clear on how obesity works and the fact that it is a relapsing medical condition and one that is with the patient for their whole life
Mortensen K, Christensen LL, Holst JJ, Orskov C
Approved GLP-1 Agonists for Weight Loss Currently, there are two GLP-1R agonists approved for the treatment of obesity, Saxenda (liraglutide) and Wegovy (semaglutide) , both developed by Novo Nordisk and approved by the FDA in 2014 and 2021, respectively
The most commonly prescribed GLP-1 drug for diabetes management and weight loss is semaglutide (sold under the brand names Ozempic and Wegovy)