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Based on a comprehensive analysis of the literature, we propose that BACH1 is a typical context-dependent transcription factor, and its function is strongly regulated by the intracellular redox state: ROS levels and heme metabolism significantly influence the expression and activity of BACH1

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Zmiz1 mutations impair neuronal differentiation and synaptic gene expression and are linked to reduced mTOR activity in other contexts, such as melanogenesis [122]

Contributors N.A served as the first author and her contributions included the initial literature search, crafting the outline of the review, as well as the writing and extensive editing of the manuscript

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RGIMS Guwahati: Where Expertise Meets Elegance At RGIMS Guwahati, under the leadership of Dr