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When GLP-1 medications slow movement through an already-inflamed bowel, the combined effect could theoretically worsen symptoms like abdominal pain, diarrhea, or obstruction risk

The benefits of GLP-1 treatments are substantial

Still, preventing GLP-2-mediated increases in portal and intestinal blood flow via L-NAME, blocks the GLP-2-mediated increase in apoB48 in the TRL fraction of plasma (Hsieh et al., 2015)

Cate Varney, the obesity medicine director for UVA Health, says in the real world, she wouldn't be surprised if her patients taking the new pill lose more weight because the pill is easier to take

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Partida-Snchez et al