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Teenagers 12 years of age or older may also be eligible if their BMI is in the 95th percentile or higher, which indicates obesity

In recent years, the incidence of PCOS was increasing (68), which could cause ratio imbalance of estrogen, insulin resistance, hyperinsulinemia, hyperandrogenemia, endometrial dysfunction, infertility, cardiovascular disease, and obesity (9)

Step 1: determine your likely dose range Most patients stabilize at 7.5 to 15 mg weekly

The meglitinides (repaglinide, nateglinide) are newer drugs that are designed to avoid this problem

There is evidence that these impurities can seriously affect patients

Patience during these early weeks ensures proper dose tolerance before advancing