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Common side effects include: Nausea Vomiting Diarrhea Stomach pain Constipation These side effects are generally mild and tend to decrease over time as the body adjusts to the medication

Pochini et al., 2013

Oxidative stress can also activate the MAP kinase pathway which results in reduced production of procollagen

By activating GIP receptors, tirzepatide enhances insulin secretion

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Immunohistofluorescence analysis Brains were collected, immediately frozen in -45 C-cold isopentane and kept at -80 C until used for immunohistofluorescence analysis

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