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Whether peripheral indices of abnormal metabolites reflect similar changes in the brain and/or are related to presumed brain events are frequently raised by the reviewers in the grant applications and manuscript submissions

Oxidative stress happens when unstable molecules called free radicals outnumber protective antioxidant molecules in the body

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(2003) Diagnostics in patients with glutathione synthetase deficiency but without mutations in the exons of the GSS gene, Hum

This is an inherited genetic disease called pyroglutamic aciduria which manifests as hemolytic anemia and metabolic acidosis, causing neurological disorders and vulnerability to bacterial infections, and which can be classified as mild, moderate or severe depending on the severity of the symptoms

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