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This precision approach may reduce side effects, improve adherence, and support safer, more effective GLP-1 therapy

Researchers delivered propionate, a fiber-derived, short-chain fatty acid, into the colons of study participants while showing them images of pizza, cakes, and chocolates, and found that increasing colonic propionate seemed to reduce brain activation in the reward centers of the brain

Key Takeaways GLP-1s are not known to commonly cause direct changes in periods

Then, HPA axis has an important impact on gut microbiota composition and neuroenteroendocrine functions, increasing gastrointestinal permeability, and contributing to the chronic low-grade inflammation [168]

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Combining a stimulant (phentermine) with a GLP-1 agonist can elevate blood pressure and heart rate unpredictably