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Increase your fluid intake: Hypovolemia, or lower levels of blood volume, may be helped, in part, by increasing the amount of water or electrolyte sports drink that you consume.[ref] Increased sodium intake: Similar to increasing fluid intake, if your sodium intake is low or your electrolyte balance is off, it can affect blood volume.[ref] Often, people with POTS are encouraged to drink sports drinks such as Gatorade

This creates an elevated TIMP:MMP ratio that correlates with collagen and elastin synthesis stimulation

It also highlighted the downregulation of DUSP4, DUSP5, and GO terms linked to MAP kinase phosphatase (MKP) activity ( Figure 5d )

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