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In particular, IL-1 and tumor necrosis factor (TNF) interact with receptors on ECs of the BBB and modulate BBB permeability in several ways, such as upregulating leukocyte adhesion molecules including P-and E-selectins and ICAM-1 that promote the migration of leukocytes through the BBB (Argaw et al., 2006

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The mechanisms are similar to those of esters

By using radiolabeled tracers that bind to specific neurotransmitter receptors or transporters, PET scans can provide detailed information about the distribution and function of neurotransmitter systems

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Amino acid transport systems