Yes fatigue improvement is one of the most commonly reported clinical outcomes of SS-31 therapy
GLP-1 is an incretin hormone that stimulates insulin secretion, suppresses glucagon, and slows gastric emptying
Overall, although the overall absolute risk increase is small (27 cases per 10,000 persons treated per year), clinical practitioners should nevertheless take into account the potential risk of gallbladder or biliary diseases associated with GLP-1RAs, especially when used at higher doses, for longer durations, and for weight loss, and in case the patient has a history of lithiasis [64]
Some individuals report improved energy and motivation as weight decreases and metabolic health improves
It is also approved for reducing cardiovascular risk in people with Type 2 diabetes and established risk factors
However, it is normal to feel hungry while taking the medication as it reduces appetite but does not get rid of it completely