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Further, increase of the AMP-to-ATP ratios, which is a direct activator of AMPK, may have been caused by proton leak via UCP2 in butyrate-feed animals, and the disruption of the activity of PPAR abolished the SCFA-induced increase of the UCP2-pAMPK-pACC pathway activity (118)

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Mistake 2: avoiding sodium entirely Years of "reduce your salt" messaging has trained many people to fear sodium