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The mean fluorescence ( F ) of each region of interest was normalised to baseline signal ( F 0 ) and expressed as F / F 0 before exporting into ClampFit (version 10.7
Participants span a range of ages, ethnicities, and geographic backgrounds
Type III tests of fixed effects were conducted using the car package 86 to evaluate the statistical significance of main effects and interaction terms
While dexamethasone only modestly reduced synovial inflammation, it failed to prevent cartilage deterioration, whereas liraglutide significantly enhanced pain thresholds, lowered synovial scores, and preserved cartilage integrity, with 60 g doses notably reducing overall joint damage [140]
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