There lies a narrow physiochemical window for the drug to effectively pass the stratum corneum which includes low melting point, low molecular weight of 600 Da, and water/octanol partition coefficient in the range of 13 [216]
Aryl propionic acid analogs form a major class of chemical compounds that, due to their ease of interaction with biological systems, are integral to a wide range of physiologically valuable molecules
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Progress and challenges towards targeted delivery of cancer therapeutics
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