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Zhang YL et al (2022) The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimers disease

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ACCORD Study Group

While CB-839 inhibited the proliferation of patient-derived glioma cell lines, it did not affect cell viability (103).In NSCLC, KEAP1 mutant NSCLC cell lines exhibit a dependence on Gln, and the GLS inhibitor CB-839 can inhibit Gln metabolism to exert anti-tumor effects (104)