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The presence of GLP-1R in MCs has been confirmed by multiple research groups, including our own 5,15,16 and ex vivo data have shown that MCs increase their action potential firing frequency after the addition of both GLP-1 and the GLP-1R agonist exendin-4 17

You cannot get enough folate from food alone , even with a diet rich in leafy greens and fortified cereals, so a supplement is essential