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Any of these stressors can cause microscopic tearing and damage to the muscle fibers and, critically, to the sarcoplasmic reticulum the intricate network within the muscle cell that stores and releases calcium

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Assumma et al., 2019

Cellular and Molecular Life Sciences 37: 913917

One essential notion he advanced is the distinction between two phases in the development of tools (technologies, institutions): a first, in which they are primarily means for the empowerment and liberation of individuals, and a second, in which they become primarily self-referential ends, ultimately oppressive and enslaving of individuals (as illustrated in, e.g., transport by the shift from bicycles and motorized public transport to mass automobility)