Who Should Not Use These Compounds and What Are the Key Risks Neither retatrutide nor tirzepatide is appropriate for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2), based on preclinical signals observed across the GLP-1 receptor agonist class
However, drug companies offer savings cards to help eligible patients pay less
Each medication follows a unique dose-escalation protocol, starting with a low dose and gradually increasing over several weeks to minimise side effects whilst achieving optimal glycaemic control or weight management
It detects what youve just eaten and tells your body to do the things it needs to do to digest and process those calories. In people with obesity or Type 2 diabetes, this system is often dysregulated, making it harder for the body to manage blood sugar and appetite
This creates a smoother way to work on your health
They work in (slightly) different ways Zepbound and Ozempic also have distinct active ingredients that work in slightly different ways Ozempic targets GLP-1 receptors, while Zepbound targets both GLP-1 and GIP receptors