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Hydrophobic interactions between Phe 9 and Y152 1.47 and L141 1.36 anchor the peptide to GLP-1R in both a conformer 1-like structure (beginning of the video) and a conformer 2-like structure (end of the video) during the simulation

showed that PIEZO-mediated mechanosensation triggers KCNN4-dependent potassium efflux, leading to NLRP3 inflammasome activation and subsequential pyroptosis [57]