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Vigorous shaking or vortexing can cause shearing forces that physically break the delicate peptide bonds or cause aggregation (clumping)

The doses heterogeneity includes the treatment duration, the different vehicles of ingestion (diet, water, isolated supplements), and the chemical forms of Se used, which increases the risk of bias between studies

These drugs work by mimicking the GLP-1 hormone naturally found in the body

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To assess the strength of the associations, they conducted a disproportionality analysisa statistical approach used in pharmacovigilance studies to detect signals of potential drug-related risks

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