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The FDA had temporarily allowed compounded GLP-1s to be prescribed in 2022 due to a shortage of the drugs

Plus, studies have found that some GLP-1 medications may increase a patients heart rate.The novelty and uncertainty surrounding the effects of GLP-1s highlight the value of long-term at-home monitoring of weight, blood pressure, and other daily biomarkers under real-world conditions

Currently, AMG-133 is undergoing a phase 2 clinical trial in adults with a BMI of 25 (overweight) or 30 (obese) and obesity-related metabolic disorders, including type 2 diabetes

These effects improve glycemic control without causing hypoglycemia, and they also delay gastric emptying and suppress appetite, contributing to weight loss