It means your body is actively using the glutathione to process and eliminate toxins
First three weeks, I noticed zero difference visually
After two weeks, there was an increase in glutathione levels and insulin sensitivity
TRT does not usually make you lazy, but some men do feel tired, flat, unmotivated, or less driven after starting testosterone therapy
Sample Weekly Schedule Here is what a typical week looks like on this stack: Monday through Friday: Morning: Topical GHK-Cu applied to face and any target areas after cleansing Any time of day: Injectable GHK-Cu 200 to 600 mcg (if using injectable form) Evening: Optional second topical GHK-Cu application One day per week (your chosen semaglutide day): Semaglutide injection at your usual time (different site from GHK-Cu) Continue GHK-Cu as normal Weekend (if using 5-day injectable schedule): Continue topical GHK-Cu Skip injectable GHK-Cu (some patients prefer a 5 days on, 2 days off schedule for convenience, though daily is also fine) Expanding the Stack Some patients choose to add additional compounds to this foundation
Recent human topical evidence A 2023 IRB-approved 21-woman topical trial of NEEL gel (a stabilized GHK-Cu topical) reported an average 28% increase in skin collagen density at 3 months, with a top quartile reporting 51%
