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Dillon DG, Gonenc A, Belleau E, Pizzagalli DA
A1: L-carnitine is an amino acid-like compound that helps transport fatty acids into the mitochondria, converting them into energy
Furthermore, because Akt suppresses GSK3, a kinase that drives neuronal apoptosis and S pathology, GLP-1/GIP agonism can attenuate downstream toxic signaling events relevant to PD neurodegeneration (Hlscher, 2025
Long-term commitment to these changes is crucial for maintaining weight loss and preventing weight regain
Most available trials to date are small and short-term, without proper blinding of participants or researchers, so theyll need much larger placebo-controlled trials in people with eating disorders before they know the drugs actual effectiveness and long-term safety