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This vital enzyme in purine metabolism converts adenosine to inosine, which leads to uric acid formation

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The result is more cost and complexity for regulators and pharmacies alike without a benefit to patients

Considering prescribing Current prescribing guidelines from the Australian Diabetes Society recommend GLP-1RAs as next-line therapy in patients who have failed to meet their glycaemic target with usual first-line therapy of metformin and as the first injectable medication before the addition of insulin

Experience slow metabolism or difficulty losing fat

2009 Jan;29(2):198206