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KPV directly inhibits NF-B signaling in intestinal epithelial cells and immune cells, making this combination particularly targeted at gut inflammation and systemic recovery

Unlike nonsteroidal anti-inflammatory drugs (NSAIDs), which may impair certain aspects of the healing response, these peptides may potentially promote healing while providing anti-inflammatory effects

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This may be due to the complex pathophysiological nature of ROS signaling in humans with comorbidities