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GLP-1RA liraglutide treatment restored lysosomal function in LAMP3 overexpressing human salivary epithelial cell line A253 cells by reducing caspase-8 expression in vitro
Diving into the supplementary appendix and related to blood pressure is eGFR
Recent studies highlight the risk for gastroparesis subsequent to GLP-1 use: While the overall risk remains below 1%, the data suggest a persistent increase relative to untreated individuals
Sequence: YAQGTFTSDYSILLDKKAQAAFIEYLLEGGPSSGAPPPS Molecular Formula: CHFNO Molecular Weight: 4,731.33 g/mol PubChem SID: 474492335 CAS Number: 2381089-83-2 Synonyms: LP3-R, LY-3437943, NOP2Y096GV, Triple agonist: GIP / GLP-1 / glucagon receptor agonist Source: Coskun et al., 2022 (Cell Metabolism) Wikipedia LP3-R (accessed 2025) Synthachem, 2024