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With my own experience in my practice and science backing it, I felt comfortable enough to start prescribing these medications myself to my patients who arent able to tolerate CPAP, Izzo says
Like the pill, GLP-1 drugs are not only changing personal health decisions, but sparking society-wide conversations around body image, equity, and access to care
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
95% CI, 0.32 to 0.60) suicidal ideation compared to non-GLP-1 RAs anti-obesity treatments [80]
Most providers recommend discontinuing use at least 12 months before attempting pregnancy
This could explain why tirzepatide (which stimulates the GIP pathway in addition to GLP -1) can be administered at higher doses than semaglutide (which only stimulates GLP-1), without amplifying the side effects typical of GLP-1 agonists (nausea, vomiting)
