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Most peptide evidence comes from animal models, small studies, and mechanistic extrapolation

Methodology The primary objective of this review is to assess the efficacy and safety of glimepiride, primarily from a clinical viewpoint, while considering clinically relevant end points

As for side effects, some individuals may experience side effects such as stomach upset or allergic reactions

doi: 10.3390/ijms23010370 11

The response of different patients to GLP-1RAs may be different, and some patients may not be able to achieve the expected hypoglycemic effect