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Relationship to Alpha-MSH KPV is the lysine-proline-valine sequence at the C-terminal end of alpha-MSH

When combined with PlexusDx compounded GLP-1 and tirzepatide options, genetic testing can support a framework for more intentional treatment selection

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Beyond these residues, there are very few interactions formed with the remainder of the N-terminal 9 residues of this peptide (Supplemental Table 3)

Major adverse cardiovascular events were also lower in patients on a GLP-1 RA (14.9% vs 18.5%