It does this by inhibiting an overload of cortisol, also referred to as the stress hormone
Comparative Risk: In patients with Type 2 Diabetes, GLP-1 RA use was associated with a 7% lower cancer incidence compared with DPP4 inhibitors
Alternating between semaglutide and tirzepatide is an approach some patients and providers explore, though insurance coverage for such protocols can be challenging to navigate
If your provider prescribes Zepbound for weight loss, you are fighting against a system that often excludes it
Appropriate candidates typically include patients who have achieved postoperative stability, demonstrate inadequate weight loss (less than 50% excess weight loss) or significant weight regain (typically defined as regaining 25% or more of lost weight), and have persistent obesity-related comorbidities despite surgical intervention
Mild side effects: Nausea (most common) Vomiting Diarrhoea or constipation Bloating and gas Fatigue Serious (rare) side effects: Thyroid tumours (seen in animal studies, rare in humans) Pancreatitis (severe abdominal pain, nausea, vomiting) Gallbladder issues (gallstones, pain after eating fatty foods) Severe dehydration (from vomiting/diarrhoea) Who Should NOT Take Tirzepatide
