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Many viruses, just like influenza, affect the oral, nasal, and upper airway and therefore lead to oxidative stress, or other conditions that deplete glutathione, increasing vulnerability to such viral infections

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Specifically, activities of the respiratory complex I and complex III were compromised and resulted in a significant increase in electron leakage to O 2 and O 2 production in mitochondria of infected cardiomyocytes and ChD hearts (Vyatkina et al., 2004