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A target of 64-80 ounces of fluid daily is appropriate for most patients (with adjustments for heart failure or kidney disease), with modifications based on activity level, climate, and gastrointestinal losses

Only affordable GLP-1s and Behavior Change will bend this curve

Deciding between semaglutide (Wegovy , Ozempic , Rybelsus ) and tirzepatide (Zepbound , Mounjaro ) comes down to cost, effectiveness, and personal preference

Cognitive Functioning/Dementia At least 5 studies (1 case-control, 1 cohort, 3 RCTs) discussed the role of GLP-1 agonists and their action in AD and dementia

compounders have turned to making generic semaglutide for markets where Novo Nordisks main patent is expiring in 2026