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4HNE and MDA were lipid peroxidation markers [84, 85], 4-HNE targets GPX4 for ubiquitin-related degradation induced ferroptosis [86], found that H

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To test this, the PRKAA1 5UTR was inserted upstream of the luciferase CDS (5UTR reporter), as described previously 38 , and transfected into shCtrl and shGDH1 cells for luciferase reporter assays