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2), yet when AMAP is administered to mice and hamsters in vivo, it has been reported that it does not cause liver injury (Tirmenstein and Nelson 1989
Exp Clin Endocrinol Diabetes 104(1):50-8
Statements Data availability statement The original contributions presented in this study are included in the article/Supplementary material, further inquiries can be directed to the corresponding authors
Florido R, Kwak L, Echouffo-Tcheugui JB, Zhang S, Michos ED, Nambi V, et al
Studies show that the C667T and A1298C variants increase the relative risk : high homocysteine, stroke, and heart disease[ref][ref][ref][ref][ref] neural tube defects and cleft lip[ref] preeclampsia and hypertension in pregnancy[ref][ref] miscarriage[ref][ref] depression or anxiety[ref][ref][ref][ref][ref] Alzheimers[ref][ref] autism spectrum disorder (C677T only according to 2026 meta-analysis)[ref] rare problems with nitrous oxide[ref], but most have no problems[ref] Lets dig into the details of what research studies and clinical trials show
Suffice it to say that a 2,000 g/day dose of cyanocobalamin is enough to ensure maximum B12 status in anyone without an extremely rare condition
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