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One year and 6 months with hyporexia, occasional nausea with no vomiting, mild intermittent pain in the epigastrium and hypogastrium, weight loss of 4kg in one year, stools with reduced consistency, and hematochezia during the past 4 months

Intracellular iron accumulation is significantly facilitated by diminished expression of ferroportin (FPN), the sole confirmed iron exporter ( - ) constitutes the initial ferroptotic signal

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