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8.2 Nanoparticles affecting TAMs and T cells There are also some nanoparticles that can simultaneously regulate TAMs and T cells to exert anti-tumor immunity in addition to the nanoparticles that regulate both NK cells and T cells, such as the DNA nanodevice E64-DNA targeting the lysosomes of TAMs in mouse can not only reprogram TAMs to improve their ability to cross-present antigens by inhibiting cysteine proteases that are specifically present within TAMs lysosomes but also inhibit tumor growth by affecting CD8 + T cells (195)

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Es spielt eine entscheidende Rolle bei der Wundheilung, Angiogenese sowie dem zellulren Remodeling und wird intensiv auf seinen Einfluss auf die Kollagensynthese, entzndungshemmende Signalwege und die Genexpression im Zusammenhang mit der Haut- und Organreparatur untersucht

doi:10.15585/mmwr.ss7007a1

L.SchjerlingP.KjaerM.HarridgeS

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