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While short-term efficacy is well-documented, concerns remain about the long-term impact of prolonged GLP-1 receptor activation, particularly in non-diabetic populations

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Signs of B12 Deficiency During GLP-1/GIP Treatment Recognising B12 deficiency can be challenging because symptoms often develop gradually and may be non-specific , particularly in patients managing diabetes or obesity who may attribute these symptoms to their underlying conditions or weight loss efforts

Am J Physiol (1997) 272(6 Pt 1):E110816