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Once central sensitization develops, even removing the original trigger may not immediately resolve the pain, because the amplification occurs in the central nervous system rather than at the periphery

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doi: 10.1111/j.1365-2788.2006.00916.xyndrome 141 ManzardoAMWeisenselNAyalaSHossainWButlerMG

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Biocontrol of mosquito vectors through herbal-derived silver nanoparticles: prospects and challenges