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Subsequently, lysates were centrifuged at 12,000 rpm for 15 min at 4 C to obtain clear supernatants

Pickart, L., Vasquez-Soltero, J

Therefore, the acidic residues of p53 TAD appear to have no significant impact on its interaction with the FOXO4 FHD, as these residues primarily contribute to DNA selectivity rather than binding to the FOXO4 FHD

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44 , 45 In addition to their direct detoxifying function, GSTs also act as inhibitors of the MAP kinase pathway, thereby contributing to the emergence of drug resistance