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Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse

Activated PPAR promotes the expression of key FAO enzymes such as CPT1 and medium-chain acyl-CoA dehydrogenase (MCAD), thereby accelerating mitochondrial FAO and supporting sustained ATP production in cardiomyocytes (216)

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This side effect is generally temporary and tends to resolve on its own [12]

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