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This article covers the biological mechanisms at play, the timing and dosage considerations that matter, and the honest limitations of the current evidence base

The exact oral bioavailability has not been formally determined, but the systemic effects observed after oral administration suggest significant absorption

doi: 10.2337/diaclin.26.2.77

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Neurophysiological assessments of the SN reticulata (SNR) and subthalamic nucleus (STN) revealed differences between MPE and L-dopa treatments