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MOTS-c improves the metabolic environment and produces measurable results in patients who have not made significant lifestyle changes

Recent studies have found that iron deficiency exists in about 50% of heart failure patients and is associated with impaired functional capacity and poorer prognosis

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10.1080/17512433.2017.1253472 Expert

The body usually adjusts within a few weeks, so side effects like diarrhea often improve over time

A final alternative to alleviate FcRn-controlled pathological mechanisms could be to alter FcRn in itself, as may be intended with a gene therapy being developed in a collaboration between Beam and Apellis for a one-time dose of gene-editing molecules targeting FcRn [436, 437]