Semaglutide GLP-1 is known as a GLP-1 receptor agonist
Heres what weve found: Effectiveness Rather than packing its capsules with as many probiotic strains as possible ( la competitor Seed), Pendulums catalog sticks to a small roster of five species with substantial research supporting their effects on gut health, metabolism, diabetes management, and weight control: , found in clinical trials to help people reduce BMI and improve diabetic biomarkers12 Akkermansia muciniphila , an effective species against common gastrointestinal (GI) pathogens16 Clostridium butyricum , shown to inhibit fat storage and reduce serum cholesterol24 Anaerobutyricum hallii , capable of supporting other beneficial bacterial species in the gut while inhibiting harmful ones9 Clostridium beijerinckii , an alleviator of irritable bowel symptoms26 Bifidobacterium infantis Pendulum includes all five species in its Metabolic Daily and Glucose Control supplements, and exclusively Akkermansia in its product of the same name
The most common side effects of these medications are gastrointestinal (GI) issues like nausea, diarrhea, and abdominal pain
The mechanism of action of berberine differs fundamentally from that of GLP-1 agonists
Last reviewed: June 1, 2026 Last updated: June 1, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
The clinic describes reviewing health history, goals, treatment options, follow-up, and monitoring, with prescription treatment considered when appropriate
