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The glutathione-deficient, cadmium-sensitive mutant, cad2 -1, of Arabidopsis thalian a is deficient in -glutamylcysteine synthetase

Simultaneously, it has been observed to modulate the expression of genes for proteoglycans and glycosaminoglycans (GAGs) like decorin, which are crucial for organizing collagen fibrils and maintaining tissue hydration in engineered skin equivalents

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Thus, like in the case of CK1, the opposite effect of PKC in erythroid precursors and mature erythrocytes can be explained by the lack of the anti-apoptotic machinery through which PKC can exert its anti-apoptotic action

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