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Purified GS were tested for canonical glutathione (Glu-Cys-Gly) synthetic capacity using a spectrophotometric assay where phosphate release from ATP is used as a molar equivalent proxy for glutathione synthesis from the substrates -glutamyl-cysteine (-EC) and glycine
Recent evidence supports a shift toward earlier, clinically based diagnosis
This may continue for several weeks or even months, as neurological recovery is often slower and more variable than haematological response
For patients with elevated liver enzymes, further workup may include hepatitis B and C serologies, iron studies, autoimmune markers, and ceruloplasmin to exclude alternative causes of liver disease
Per the company, the new brochure can be found on the pharmacy counter and is available to all customers
PLoS ONE 15 , e0234552 (2020)
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