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For this role, SMAX1 D2 has been repurposed from an ATPase domain into a binding module through the loss of its nucleotide binding site and the use of its pore loop for allosteric stabilisation of the association between the F-box and the SL-bound receptor

In laboratory settings, researchers utilize this compound in in-vitro and biochemical model systems to examine dual-receptor agonism, pathway interaction, and peptide-mediated regulatory mechanisms associated with metabolic and endocrine signaling networks

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