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Put together, the four ingredients span the spectrum from real human trials in a different context (T4) through solid topical cosmetic data (GHK-Cu) to strong animal, thin human (BPC-157) and animal-only (KPV)

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Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 should not use GLP-1 agonists, as animal studies suggested potential thyroid C-cell effects (though human data remain reassuring)